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Article

Xenobiotic effects in the ovary: temporary versus permanent infertility

22 Jan 2014

Abstract excerpt

INTRODUCTION: Damage caused by xenobiotic compounds to the ovaries is a subject of concern because of their critical role in reproduction. Female mammals are born with a finite number of germ cells (oocytes) encased in primordial follicles. Xenobiotic-induced damage to primordial follicles can result in early ovarian failure (premature menopause). Alternatively, damage affecting larger growing follicles can...

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PMID: 24450963
DOI: 10.1517/17425255.2014.880690

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