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Silica Nanoparticles Promote Apoptosis in Ovarian Granulosa Cells via Autophagy Dysfunction

8 Mar 2023

Abstract excerpt

Although silica nanoparticles (SNPs) are generally thought to be biocompatible and safe, the adverse effects of SNPs were also reported in previous studies. SNPs cause follicular atresia via the induction of ovarian granulosa cell apoptosis. However, the mechanisms for this phenomenon are not well understood. This study focuses on exploring the relationship between autophagy and apoptosis induced by SNPs in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36982262
DOI: 10.3390/ijms24065189

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