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Article

Genetic abnormalities in sporadic parathyroid adenomas.

The Journal of clinical endocrinology and metabolism - 1 Aug 1990

Friedman E, Bale A E, Marx S J, Norton J A, Arnold A, Tu T, Aurbach G D, Spiegel A M

Abstract excerpt

We analyzed genomic DNA from 43 sporadic benign parathyroid adenomas for rearrangements of the PTH gene, and for point mutations of the H-ras (codons 12, 13, and 61), N-ras (codons 12, 13, and 61), and K-ras (codons 12 and 13) genes. One of 43 parathyroid adenomas showed a chromosome 11 rearrange...

Topics

Adenoma
Blotting, Southern
Chromosomes, Human, Pair 11
Codon
DNA
Gene Rearrangement
Genes, ras
Humans
Hyperparathyroidism
Mutation
Parathyroid Hormone
Parathyroid Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2199477
DOI: 10.1210/jcem-71-2-293

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2199477-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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