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Article

Genetic abnormalities in sporadic parathyroid adenomas.

The Journal of clinical endocrinology and metabolism - 1 Aug 1990

Friedman E, Bale A E, Marx S J, Norton J A, Arnold A, Tu T, Aurbach G D, Spiegel A M

Abstract excerpt

We analyzed genomic DNA from 43 sporadic benign parathyroid adenomas for rearrangements of the PTH gene, and for point mutations of the H-ras (codons 12, 13, and 61), N-ras (codons 12, 13, and 61), and K-ras (codons 12 and 13) genes. One of 43 parathyroid adenomas showed a chromosome 11 rearrangement involving both the PTH gene on the short arm of chromosome 11 (at band p15) and a locus on the long arm (11q13)....

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Source

Identifiers

PMID: 2199477
DOI: 10.1210/jcem-71-2-293

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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