Article
Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia.
Haematologica - 1 Feb 2012
Fried Isabella, Bodner Claudia, Pichler Monika M, Lind Karin, Beham-Schmid Christine, Quehenberger Franz, Sperr Wolfgang R, Linkesch Werner, Sill Heinz, Wölfler Albert
Abstract excerpt
The recent identification of DNMT3A mutations in de novo acute myeloid leukemia prompted us to determine their frequency, patterns and clinical impact in a cohort of 98 patients with either therapy-related or secondary acute myeloid leukemia developing from an antecedent hematologic disorder. We...
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