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Article

Mast cells contribute to scar formation during fetal wound healing.

The Journal of investigative dermatology - 1 Feb 2012

Wulff Brian C, Parent Allison E, Meleski Melissa A, DiPietro Luisa A, Schrementi Megan E, Wilgus Traci A

Abstract excerpt

Scar formation is a potentially detrimental process of tissue restoration in adults, affecting organ form and function. During fetal development, cutaneous wounds heal without inflammation or scarring at early stages of development; however, they begin to heal with significant inflammation and scarring as the skin becomes more mature. One possible cell type that could regulate the change from scarless to fibrotic...

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Identifiers

PMID: 21993557
DOI: 10.1038/jid.2011.324
PMCID: PMC3258379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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