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Article

Down-regulation of decorin, a transforming growth factor-beta modulator, is associated with scarless fetal wound healing.

Journal of pediatric surgery - 1 Nov 2001

Beanes S R, Dang C, Soo C, Wang Y, Urata M, Ting K, Fonkalsrud E W, Benhaim P, Hedrick M H, Atkinson J B, Lorenz H P

Abstract excerpt

PURPOSE: Transforming growth factor beta (TGF-beta) bioactivity has been implicated as a potential regulator of the transition from scarless healing to scar formation in fetal wounds. Decorin is an extracellular matrix proteoglycan that regulates TGF-beta bioactivity and assists in collagen fibrillogenesis. To determine its role in scarless repair, the authors examined decorin expression in fetal fibroblasts,...

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Source

Identifiers

PMID: 11685698
DOI: 10.1053/jpsu.2001.27946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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