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Article

A mouse fetal skin model of scarless wound repair.

Journal of visualized experiments : JoVE - 16 Jan 2015

Walmsley Graham G, Hu Michael S, Hong Wan Xing, Maan Zeshaan N, Lorenz H Peter, Longaker Michael T

Abstract excerpt

Early in utero, but not in postnatal life, cutaneous wounds undergo regeneration and heal without formation of a scar. Scarless fetal wound healing occurs across species but is age dependent. The transition from a scarless to scarring phenotype occurs in the third trimester of pregnancy in humans and around embryonic day 18 (E18) in mice. However, this varies with the size of the wound with larger defects...

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Identifiers

PMID: 25650841
DOI: 10.3791/52297
PMCID: PMC4354537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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