Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Olfaction and imaging biomarkers in premotor LRRK2 G2019S-associated Parkinson disease.

Neurology - 12 Feb 2013

Sierra Maria, Sánchez-Juan Pascual, Martínez-Rodríguez María Isabel, González-Aramburu Isabel, García-Gorostiaga Inés, Quirce María Remedios, Palacio Enrique, Carril José Manuel, Berciano José, Combarros Onofre, Infante Jon

Abstract excerpt

OBJECTIVE: To ascertain in a cross-sectional study whether substantia nigra (SN) echogenicity, olfaction, and dopamine transporter (DaT)-SPECT are reliable premotor biomarkers in a cohort of asymptomatic carriers of the LRRK2 G2019S mutation (AsG2019S+). METHODS: These biomarkers were evaluated in 49 AsG2019S+ patients, and we also studied olfaction and SN echogenicity in 29 patients with G2019S-associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Glycine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Olfaction Disorders

Share to Serine

Share to Substantia Nigra

Share to Tomography, Emission-Computed, Single-Photon

Source

Identifiers

PMID: 23325906
DOI: 10.1212/WNL.0b013e31828250d6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Olfaction and imaging biomarkers in premotor LRRK2 G2019S-associated Parkinson disease.PMID 23325906Read ↗

Clinical and imaging markers in premotor LRRK2 G2019S mutation carriers.Semantic proximity Read ↗

Substantia nigra hyperechogenicity with LRRK2 G2019S mutations.Semantic proximity Read ↗

Clinical and brain imaging characteristics in leucine-rich repeat kinase 2-associated PD and asymptomatic mutation carriers.Semantic proximity Read ↗

Transcranial sonography and functional imaging in glucocerebrosidase mutation Parkinson disease.Semantic proximity Read ↗

Hyposmia in G2019S LRRK2-related parkinsonism: clinical and pathologic data.Semantic proximity Read ↗

Voice changes in prodromal Parkinson's disease: Is a new biomarker within earshot?Semantic proximity Read ↗

Brain parenchyma sonography detects preclinical parkinsonism.Semantic proximity Read ↗

Prospective clinical and DaT-SPECT imaging in premotor LRRK2 G2019S-associated Parkinson disease.Semantic proximity Read ↗

Sonographic alteration of substantia nigra is related to parkinsonism-predominant course of X-linked dystonia-parkinsonism.Semantic proximity Read ↗

Gaucher disease ascertained through a Parkinson's center: imaging and clinical characterization.Semantic proximity Read ↗

Transcranial sonography reveals striatal neurodegeneration in female XDP-causing variant carriersSemantic proximity Read ↗

Transcranial sonography in patients with Parkinson's disease with glucocerebrosidase mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.