Article
Protective HIV-specific CD8+ T cells evade Treg cell suppression.
Nature medicine - 17 Jul 2011
Elahi Shokrollah, Dinges Warren L, Lejarcegui Nicholas, Laing Kerry J, Collier Ann C, Koelle David M, McElrath M Juliana, Horton Helen
Abstract excerpt
Specific human leukocyte antigens (HLAs), notably HLA-B*27 and HLA-B*57 allele groups, have long been associated with control of HIV-1. Although the majority of HIV-specific CD8(+) T cells lose proliferative capacity during chronic infection, T cells restricted by HLA-B*27 or HLA-B*57 allele grou...
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