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Contribution of the Lipopolysaccharide to Resistance of Shigella flexneri 2a to Extreme Acidity

3 Oct 2011

Abstract excerpt

Shigella flexneri is endemic in most underdeveloped countries, causing diarrheal disease and dysentery among young children. In order to reach its target site, the colon, Shigella must overcome the acid environment of the stomach. Shigella is able to persist in this stressful environment and, because of this ability it can initiate infection following the ingestion of very small inocula. Thus, acid resistance is...

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PMID: 21984920
DOI: 10.1371/journal.pone.0025557

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