Article
Inactivation of Lipopolysaccharide-Biosynthesizing Genes Altered Lipids Composition and Intensity in Cronobacter sakazakii.
Pathogens (Basel, Switzerland) - 23 Nov 2024
Hu Xiaoqing, Yang Xi, Wu Shuyan, Lu Xuan, Ma Yuan, Tang Ziyi, Wang Xiaoyuan, Huang Xiaodong, Wang Shuiping
Abstract excerpt
Gram-negative bacteria possess an asymmetric outer membrane, where the outer leaflet consists of LPSs and the inner leaflet comprises phospholipids. Cronobacter sakazakii, an opportunistic milk-borne pathogen that causes severe neonatal meningitis and bacteremia, displays diverse lipopolysaccharide (LPS) structures. As a barrier of the bacterial cell, LPSs likely influenced C. sakazakii resistance to environment...
Topics
- Cronobacter sakazakii
- Lipopolysaccharides
- Mutation
- Lipidomics
- Humans
- Lipids
- Lipid Metabolism
- Bacterial Proteins