Article
Expression of genes involved in susceptibility to multifactorial autoimmune diseases: estimating genotype effects.
International journal of immunogenetics - 1 Jun 2013
de Almeida E Rocha Amazonas, Petzl-Erler M L
Abstract excerpt
Several single nucleotide polymorphisms (SNPs) have been associated with susceptibility to autoimmune diseases, but the mechanisms responsible for the associations are poorly understood. To test the hypothesis that the variation of the basal levels of the gene products is significantly influenced by genetic polymorphism, we investigated whether SNPs in genes CD40, CD28, CTLA4, CD80, CD86, BAFF and IL6 are...
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