Article
Interactions between genetic variants and dietary lipid composition: effects on circulating LDL cholesterol in children.
The American journal of clinical nutrition - 1 Dec 2014
Ahola-Olli Ari V, Pitkänen Niina, Kettunen Johannes, Oikonen Mervi K, Mikkilä Vera, Lehtimäki Terho, Kähönen Mika, Pahkala Katja, Niinikoski Harri, Kangas Antti J, Soininen Pasi, Ala-Korpela Mika, Viikari Jorma S, Rönnemaa Tapani, Simell Olli, Raitakari Olli T
Abstract excerpt
BACKGROUND: Elevated serum low-density lipoprotein (LDL) cholesterol is a predictor of cardiovascular disease events, and the quality of dietary fat is known to influence serum concentrations of LDL cholesterol in children. Interindividual differences in response to diet exist, but the underlying genetic factors remain largely unknown. OBJECTIVE: We aimed to identify genetic variants that modify the variation in...
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