Article
No evidence of association between 8q24 and susceptibility to nonsyndromic cleft lip with or without palate in Japanese population.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Nov 2012
Hikida Masanori, Tsuda Masayoshi, Watanabe Akira, Kinoshita Akira, Akita Sadanori, Hirano Akiyoshi, Uchiyama Takeshi, Yoshiura Koh-ichiro
Abstract excerpt
OBJECTIVE: Recent genome-wide association studies identified susceptibility loci for nonsyndromic cleft lip with or without cleft palate (NSCL±P) on 8q24.21, 10q25.3, 13q31.1, 15q13.3, 17q22, and 18q22 in populations of European origin. The purpose of this study was to determine, using DNA samples, whether 8q24.21 was a susceptibility locus for the development of NSCL±P in Japanese patients. METHODS: We used DNA...
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