Article
Association study using single nucleotide polymorphisms in the estrogen receptor beta (ESR2) gene for preeclampsia.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Dec 2004
Maruyama Aya, Nakayama Tomohiro, Sato Naoyuki, Mizutani Yoshihiro, Furuya Kiyohide, Yamamoto Tatsuo
Abstract excerpt
The pathophysiology of preeclampsia (PE) remains uncertain despite many research efforts. Actual hypotheses seek to explain the vascular damage that characterizes the disease. Recently, it was reported that the mouse disrupted estrogen receptor beta (ESR2) gene was associated with abnormal vascular function and hypertension. Moreover, some investigators have reported that subjects with a family history of...
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