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Article

Promoter Methylation Regulates Estrogen Receptor 2 in Human Endometrium and Endometriosis1

11 Jul 2007

Abstract excerpt

Steroid receptors in the stromal cells of endometrium and its disease counterpart tissue endometriosis play critical physiologic roles. We found that mRNA and protein levels of estrogen receptor 2 (ESR2) were strikingly higher, whereas levels of estrogen receptor 1 (ESR1), total progesterone receptor (PGR), and progesterone receptor B (PGR B) were significantly lower in endometriotic versus endometrial stromal...

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PMID: 17625110
DOI: 10.1095/biolreprod.107.061804

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