Article
Phosphorylated T567 ezrin is associated with merlin expression in KIT-mutant gastrointestinal stromal tumors.
Molecular medicine reports - 1 Jan 2012
Weng Wen-Hui, Yeh Chun-Nan, Cheng Yung-Feng, Lenka Govinda, Liaw Yi-Wei
Abstract excerpt
Membrane-cytoskeleton linker organizer ezrin is a member of the ERM (ezrin-radixin-moesin) protein family. It has been suggested as an important element in the oncogenic process, particularly in conferring a metastatic ability on tumor cells. We hypothesized that the KIT oncogenic form is one of the proteins that modulates expression of the ezrin protein via...
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