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Article

EZR promotes pancreatic cancer proliferation and metastasis by activating FAK/AKT signaling pathway

9 Oct 2021

Abstract excerpt

BACKGROUND: As a member of the ERM (ezrin-radixin-moesin) protein family, EZR has been recognized as a regulator of adhesion signal pathways by researchers. Moreover, EZR was thought to play irreplaceable roles in invasion and metastasis of versatile cancers. In this study, we managed to undermine the effect of EZR on proliferation and metastasis in pancreatic cancer (PC). METHODS: To analyze the impact of EZR...

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PMID: 34627255
DOI: 10.1186/s12935-021-02222-1

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