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Article

Prognostic implications of ezrin and phosphorylated ezrin expression in non-small cell lung cancer

15 Mar 2014

Abstract excerpt

BACKGROUND: The cytoskeletal organizer ezrin is a member of the ezrin-radixin-moesin (ERM) family and plays important roles in not only cell motility, cell adhesion, and apoptosis, but also in various cell signaling pathways. Phosphorylation at Thr-567 and Tyr-353 are key regulatory events in the transition of the dormant to active form of ezrin. This study investigated the prognostic implications of ezrin and...

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PMID: 24629131
DOI: 10.1186/1471-2407-14-191

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