Article
The KCNE genes in hypertrophic cardiomyopathy: a candidate gene study.
Journal of negative results in biomedicine - 3 Oct 2011
Hedley Paula L, Haundrup Ole, Andersen Paal S, Aidt Frederik H, Jensen Morten, Moolman-Smook Johanna C, Bundgaard Henning, Christiansen Michael
Abstract excerpt
BACKGROUND: The gene family KCNE1-5, which encode modulating β-subunits of several repolarising K+-ion channels, has been associated with genetic cardiac diseases such as long QT syndrome, atrial fibrillation and Brugada syndrome. The minK peptide, encoded by KCNE1, is attached to the Z-disc of the sarcomere as well as the T-tubules of the sarcolemma. It has been suggested that minK forms part of an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.