Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

S38G single-nucleotide polymorphism at the KCNE1 locus is associated with heart failure.

Heart rhythm - 1 Mar 2010

Fatini Cinzia, Sticchi Elena, Marcucci Rossella, Verdiani Valerio, Nozzoli Carlo, Vassallo Cristina, Emdin Michele, Abbate Rosanna, Gensini Gian Franco

Abstract excerpt

BACKGROUND: Prolongation of the action potential duration, whose major determinants are the delayed-rectifier potassium currents, is a hallmark of failing ventricular myocardium. Genetic variants in the KCNE1 gene, encoding for the beta-subunit (minK) of a slowly activated cardiac potassium channel (I(ks)), may impair myocardial repolarization. Experimental data demonstrated a higher KCNE1 expression in heart...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Heart Failure

Share to Polymorphism, Single Nucleotide

Share to Potassium Channels, Voltage-Gated

Share to Young Adult

Source

Identifiers

PMID: 20185111
DOI: 10.1016/j.hrthm.2009.11.032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

S38G single-nucleotide polymorphism at the KCNE1 locus is associated with heart failure.PMID 20185111Read ↗

Association between KCNE1 G38S gene polymorphism and risk of atrial fibrillation: A PRISMA-compliant meta-analysis.Semantic proximity Read ↗

Latent pathogenicity of the G38S polymorphism of KCNE1 K+ channel modulator.Semantic proximity Read ↗

Association between KCNE1 (G38S) genetic polymorphism and non-valvular atrial fibrillation in an Uygur population.Semantic proximity Read ↗

The common non-synonymous variant G38S of the KCNE1-(minK)-gene is not associated to QT interval in Central European Caucasians: results from the KORA study.Semantic proximity Read ↗

[Association of single nucleotide polymorphism of KCNE1 and KCNE4 gene with atrial fibrillation in Xinjiang Uygur and Han population].Semantic proximity Read ↗

Correlation analysis between the delayed rectifier potassium channel KCNE1 (G38S) polymorphism and atrial fibrillation among the senior Uygur population in Xinjiang.Semantic proximity Read ↗

Possible association of the human KCNE1 (minK) gene and QT interval in healthy subjects: evidence from association and linkage analyses in Israeli families.Semantic proximity Read ↗

Mutation in KCNE1 associated to early repolarization syndrome by modulation of slowly activating delayed rectifier K+ current.Semantic proximity Read ↗

Association of the human minK gene 38G allele with atrial fibrillation: evidence of possible genetic control on the pathogenesis of atrial fibrillation.Semantic proximity Read ↗

Analysis of minK and eNOS genes as candidate loci for predisposition to non-valvular atrial fibrillation.Semantic proximity Read ↗

Common variants in myocardial ion channel genes modify the QT interval in the general population: results from the KORA study.Semantic proximity Read ↗

The KCNE genes in hypertrophic cardiomyopathy: a candidate gene study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.