Article
Comparative performance evaluation of hepatitis C virus genotyping based on the 5' untranslated region versus partial sequencing of the NS5B region of brazilian patients with chronic hepatitis C.
Virology journal - 3 Oct 2011
Nakatani Sueli M, Santos Carlos A, Riediger Irina N, Krieger Marco A, Duarte Cesar A B, do Carmo Debur Maria, Carrilho Flair J, Ono Suzane K
Abstract excerpt
BACKGROUND: Genotyping of hepatitis C virus (HCV) has become an essential tool for prognosis and prediction of treatment duration. The aim of this study was to compare two HCV genotyping methods: reverse hybridization line probe assay (LiPA v.1) and partial sequencing of the NS5B region. METHODS: Plasma of 171 patients with chronic hepatitis C were screened using both a commercial method (LiPA HCV Versant,...
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