Article
Thyroid hormone promotes remodeling of coronary resistance vessels.
PloS one - 1 Jan 2011
Savinova Olga V, Liu Yingheng, Aasen Garth A, Mao Kai, Weltman Nathan Y, Nedich Brett L, Liang Qiangrong, Gerdes A Martin
Abstract excerpt
Low thyroid hormone (TH) function has been linked to impaired coronary blood flow, reduced density of small arterioles, and heart failure. Nonetheless, little is known about the mechanisms by which THs regulate coronary microvascular remodeling. The current study examined the initial cellular events associated with coronary remodeling induced by triiodothyronine (T3) in hypothyroid rats. Rats with established...
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