Article
Effect of hypothyroidism on myosin heavy chain expression in rat pharyngeal dilator muscles.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jul 1992
Petrof B J, Kelly A M, Rubinstein N A, Pack A I
Abstract excerpt
Although the association between hypothyroidism and obstructive sleep apnea is well established, the effect of thyroid hormone deficiency on contractile proteins in pharyngeal dilator muscles responsible for maintaining upper airway patency is unknown. In the present study, the effects of hypothyroidism on myosin heavy chain (MHC) expression were examined in the sternohyoid, geniohyoid, and genioglossus muscles...
Topics
- Animals
- Blotting, Northern
- Enzyme-Linked Immunosorbent Assay
- Gene Expression Regulation
- Hypothyroidism
- Immunohistochemistry
- Male
- Myosins
- Neck Muscles
- Pharyngeal Muscles
- Phenotype