Article
Signaling mechanisms in thyroid hormone-induced cardiac hypertrophy.
Vascular pharmacology - 1 Jan 2000
Ojamaa Kaie
Abstract excerpt
Cardiac hypertrophy is a significant independent risk factor for increased mortality, comprising of maladaptive changes in cellular, molecular and metabolic processes that ultimately lead to heart failure. However, cardiac hypertrophy represents a continuum from physiological to compensatory to pathological hypertrophy, so that treatment modalities aimed to shift hypertrophy towards the physiological phenotype...
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