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Article

D-Ribose Induces Cellular Protein Glycation and Impairs Mouse Spatial Cognition

8 Sept 2011

Abstract excerpt

BACKGROUND: D-ribose, an important reducing monosaccharide, is highly active in the glycation of proteins, and results in the rapid production of advanced glycation end products (AGEs) in vitro. However, whether D-ribose participates in glycation and leads to production of AGEs in vivo still requires investigation. METHODOLOGY/PRINCIPAL FINDINGS: Here we treated cultured cells and mice with D-ribose and D-glucose...

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PMID: 21966363
DOI: 10.1371/journal.pone.0024623

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