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Article

Guanosine 3'-diphosphate 5'-diphosphate is not required for growth rate-dependent control of rRNA synthesis in Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990

Gaal T, Gourse R L

Abstract excerpt

rRNA synthesis in Escherichia coli is subject to at least two regulation systems, growth rate-dependent control and stringent control. The inverse correlation between rRNA synthesis rates and guanosine 3'-diphosphate 5'-diphosphate (ppGpp) levels under various physiological conditions has led to the supposition that ppGpp is the mediator of both control mechanisms by inhibiting transcription from rrn P1...

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Identifiers

PMID: 2196571
DOI: 10.1073/pnas.87.14.5533
PMCID: PMC54359

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