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Article

Stringent control and growth-rate-dependent control have nonidentical promoter sequence requirements.

Proceedings of the National Academy of Sciences of the United States of America - 14 Feb 1995

Josaitis C A, Gaal T, Gourse R L

Abstract excerpt

Escherichia coli uses at least two regulatory systems, stringent control and growth-rate-dependent control, to adjust rRNA output to amino acid availability and the steady-state growth rate, respectively. We examined transcription from rrnB P1 promoters containing or lacking the cis-acting UP element and FIS protein binding sites after amino acid starvation. The "core promoter" responds to amino acid starvation...

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Identifiers

PMID: 7862645
DOI: 10.1073/pnas.92.4.1117
PMCID: PMC42649

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Source receipt: pubmed, retrieved 7 Sept 2026.

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