Strongly reduced phage Qbeta replication, but normal phage MS2 replication in an Escherichia coli K12 mutant with inactivated Qbeta host factor (hfq) gene.

doi:10.1006/viro.1996.8302

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Article

Strongly reduced phage Qbeta replication, but normal phage MS2 replication in an Escherichia coli K12 mutant with inactivated Qbeta host factor (hfq) gene.

Virology - 6 Jan 1997

Su Q, Schuppli D, Tsui HcT, Winkler M E, Weber H

Abstract excerpt

RNA phage production was observed in Escherichia coli hfq mutant strains transformed with plasmids containing genomic cDNA of phages Qbeta or MS2. Qbeta production was reduced 5000-fold in an insertional mutant containing an omega cassette in the middle of hfq, but was unaffected in a mutant with...

Topics

Carrier Proteins
Coliphages
Escherichia coli
Escherichia coli Proteins
Host Factor 1 Protein
Integration Host Factors
Levivirus
Mutation
RNA Phages
Virus Replication

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