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Fine Mapping of a cis -Acting Sequence Element in Yellow Fever Virus RNA That Is Required for RNA Replication and Cyclization

13 Jan 2003

Abstract excerpt

We present fine mapping of a cis-acting nucleotide sequence found in the 5' region of yellow fever virus genomic RNA that is required for RNA replication. There is evidence that this sequence interacts with a complementary sequence in the 3' region of the genome to cyclize the RNA. Replicons were constructed that had various deletions in the 5' region encoding the capsid protein and were tested for their ability...

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PMID: 12525663
DOI: 10.1128/jvi.77.3.2265-2270.2003

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