Article
[Pharmacogenetics of insulin secretagogue antidiabetics].
Orvosi hetilap - 9 Oct 2011
Winkler Gábor, Gerô László
Abstract excerpt
Type 2 diabetes is making up to 90% of the all diabetic cases. In addition to insulin resistance, insufficient B-cell function also plays an important role in the pathogenesis of the disease. The insufficient production and secretion of insulin can be increased by secretagogue drugs, like sulfonylureas and incretin mimetics/enhancers. In recent years growing number of genetic failures of the B-cells has been...
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