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Ion Transporters, Channelopathies, and Glucose Disorders

27 May 2019

Abstract excerpt

Ion channels and transporters play essential roles in excitable cells including cardiac, skeletal and smooth muscle cells, neurons, and endocrine cells. In pancreatic beta-cells, for example, potassium KATP channels link the metabolic signals generated inside the cell to changes in the beta-cell membrane potential, and ultimately regulate insulin secretion. Mutations in the genes encoding some ion transporter and...

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PMID: 31137773
DOI: 10.3390/ijms20102590

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