Article
Clinical and Genetic Characteristics of ABCC8 Nonneonatal Diabetes Mellitus: A Systematic Review.
Journal of diabetes research - 1 Jan 2021
Li Meng, Han Xueyao, Ji Linong
Abstract excerpt
OBJECTIVES: Diabetes mellitus (DM) is a major chronic metabolic disease in the world, and the prevalence has been increasing rapidly in recent years. The channel of KATP plays an important role in the regulation of insulin secretion. The variants in ABCC8 gene encoding the SUR1 subunit of KATP could cause a variety of phenotypes, including neonatal diabetes mellitus (ABCC8-NDM) and ABCC8-induced nonneonatal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
