Article
Genetic polymorphisms in diabetes: influence on therapy with oral antidiabetics.
Acta pharmaceutica (Zagreb, Croatia) - 1 Dec 2010
Glamočlija Una, Jevrić-Čaušević Adlija
Abstract excerpt
Due to new genetic insights, etiologic classification of diabetes is under constant scrutiny. Hundreds, or even thousands, of genes are linked with type 2 diabetes. Three common variants (Lys23 of KCNJ11, Pro12 of PPARG, and the T allele at rs7903146 of TCF7L2) have been shown to be predisposed to type 2 diabetes mellitus across many large studies. Individually, each of these polymorphisms is only moderately...
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