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Article

Molecular determinants of arenavirus Z protein homo-oligomerization and L polymerase binding.

Journal of virology - 1 Dec 2011

Loureiro Maria Eugenia, Wilda Maximiliano, Levingston Macleod Jesica M, D'Antuono Alejandra, Foscaldi Sabrina, Marino Buslje Cristina, Lopez Nora

Abstract excerpt

The arenavirus Z is a zinc-binding RING protein that has been implicated in multiple functions during the viral life cycle. These roles of Z involve interactions with viral and cellular proteins that remain incompletely understood. In this regard, Z inhibits viral RNA transcription and replication through direct interaction with the viral L polymerase. Here, we defined the L-binding domain of Tacaribe virus...

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Identifiers

PMID: 21957305
DOI: 10.1128/JVI.05691-11
PMCID: PMC3209362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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