Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a Cullin5-ElonginB-ElonginC E3 complex in degradation of feline immunodeficiency virus Vif-mediated feline APOBEC3 proteins.

Journal of virology - 1 Dec 2011

Wang Jiawen, Zhang Wenyan, Lv Mingyu, Zuo Tao, Kong Wei, Yu Xianghui

Abstract excerpt

Various feline APOBEC3 (fA3) proteins exhibit broad antiviral activities against a wide range of viruses, such as feline immunodeficiency virus (FIV), feline foamy virus (FFV), and feline leukemia virus (FeLV), as well as those of other species. This activity can be counteracted by the FIV Vif protein, but the mechanism by which FIV Vif suppresses fA3s is unknown. In the present study, we demonstrated that FIV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to APOBEC Deaminases
Share to Cats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cullin Proteins

Share to Cytidine Deaminase

Share to Cytosine Deaminase

Share to Gene Products, vif

Share to Immunodeficiency Virus, Feline

Share to Immunoprecipitation

Source

Open in PubMed Open full text

Identifiers

PMID: 21957297
DOI: 10.1128/JVI.05218-11
PMCID: PMC3209414

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a Cullin5-ElonginB-ElonginC E3 complex in degradation of feline immunodeficiency virus Vif-mediated feline APOBEC3 proteins.PMID 21957297Read ↗

Characterization of Vif domains that mediate Feline Immunodeficiency Virus antagonism of APOBEC3-H and APOBEC3-CH restrictionSemantic proximity Read ↗

Feline Immunodeficiency Virus Evolutionarily Acquires Two Proteins, Vif and Protease, Capable of Antagonizing Feline APOBEC3Semantic proximity Read ↗

Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.Semantic proximity Read ↗

Advances in the Structural Understanding of Vif ProteinsSemantic proximity Read ↗

Feline Immunodeficiency Virus Vif N-Terminal Residues Selectively Counteract Feline APOBEC3s.Semantic proximity Read ↗

Distinct Determinants in HIV-1 Vif and Human APOBEC3 Proteins Are Required for the Suppression of Diverse Host Anti-Viral ProteinsSemantic proximity Read ↗

Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function.Semantic proximity Read ↗

Core-Binding Factor Subunit Beta Is Not Required for Non-Primate Lentiviral Vif-Mediated APOBEC3 DegradationSemantic proximity Read ↗

Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly.Semantic proximity Read ↗

Cytidine Deaminases as a Weapon Against Retroviruses and a New Target for Antiviral TherapySemantic proximity Read ↗

Evolutionary Paradigms from Ancient and Ongoing Conflicts between the Lentiviral Vif Protein and Mammalian APOBEC3 EnzymesSemantic proximity Read ↗

Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional ActivitiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.