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Article

Clear cell mesotheliomas with inactivating VHL mutations and near-haploid genomic features.

Genes, chromosomes & cancer - 1 May 2023

Michal Michael, Kravtsov Oleksandr, Ross Jeffrey S, Skanderová Daniela, Martínek Petr, Mosaieby Elaheh, Mata Douglas A, Williams Erik A, Hung Yin P

Abstract excerpt

Clear cell mesothelioma is uncommon and shows predominance of clear cells with resemblance to clear cell carcinomas. Clinicopathologic and molecular descriptions of clear cell mesothelioma remained limited. In this study, we identified an index patient with clear cell mesothelioma, confirmed by immunohistochemical and ultrastructural studies. Targeted next-generation sequencing revealed the presence of an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 36515470
DOI: 10.1002/gcc.23119

Genes

VHL
BAP1
CDKN2A
CDKN2B
NF2
PTEN
SETD2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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