Article
Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs.
PloS one - 1 Jan 2013
Gupta Vipin, Vinay Donipadi Guru, Sovio Ulla, Rafiq Sajjad, Kranthi Kumar Madamchetty Venkata, Janipalli Charles Spurgeon, Evans David, Mani Kulathu Radha, Sandeep Madana Narasimha, Taylor Amy, Kinra Sanjay, Sullivan Ruth, Bowen Liza, Timpson Nicholas, Smith George Davey, Dudbridge Frank, Prabhakaran Dorairaj, Ben-Shlomo Yoav, Reddy Kolli Srinath, Ebrahim Shah, Chandak Giriraj Ratan
Abstract excerpt
Obesity is an established risk factor for type 2 diabetes (T2D) and they are metabolically related through the mechanism of insulin resistance. In order to explore how common genetic variants associated with T2D correlate with body mass index (BMI), we examined the influence of 25 T2D associated loci on obesity risk. We used 5056 individuals (2528 sib-pairs) recruited in Indian Migration Study and conducted...
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