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Article

JC polyomavirus in the aetiology and pathophysiology of glial tumours.

Neurosurgical review - 1 Jan 2016

Eftimov Tihomir, Enchev Yavor, Tsekov Iliya, Simeonov Plamen, Kalvatchev Zlatko, Encheva Elitsa

Abstract excerpt

Glial brain tumours with their poor prognosis, limited treatment modalities and unclear detailed pathophysiology represent a significant health concern. The purpose of the current study was to investigate and describe the possible role of the human polyomavirus JC as an underlying cancerogenic or co-cancerogenic factor in the complex processes of glial tumour induction and development. Samples from 101 patients...

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PMID: 26560882
DOI: 10.1007/s10143-015-0676-5

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