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Reconsidering the Sporulation Characteristics of Hypervirulent Clostridium difficile BI/NAP1/027

15 Sept 2011

Abstract excerpt

Clostridium difficile is the leading cause of antibiotic-associated diarrhoea and a major burden to healthcare services worldwide. In recent years, C. difficile strains belonging to the BI/NAP1/027 type have become highly represented among clinical isolates. These so-called 'hypervirulent' strains are associated with outbreaks of increased disease severity, higher relapse rates and an expanded repertoire of...

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PMID: 21949780
DOI: 10.1371/journal.pone.0024894

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