Article
Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes.
PloS one - 1 Jan 2011
Rees Simon D, Hydrie M Zafar I, O'Hare J Paul, Kumar Sudhesh, Shera A Samad, Basit Abdul, Barnett Anthony H, Kelly M Ann
Abstract excerpt
BACKGROUND: The Meta-Analysis of Glucose and Insulin related traits Consortium (MAGIC) recently identified 16 loci robustly associated with fasting glucose, some of which were also associated with type 2 diabetes. The purpose of our study was to explore the role of these variants in South Asian populations of Punjabi ancestry, originating predominantly from the District of Mirpur, Pakistan. METHODOLOGY/PRINCIPAL...
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