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Assessment of genetic risk of type 2 diabetes among Pakistanis based on GWAS-implicated loci.

Gene - 30 May 2021

Sabiha Bibi, Bhatti Attya, Fan Kang-Hsien, John Peter, Aslam Muhammad Muaaz, Ali Johar, Feingold Eleanor, Demirci F Yesim, Kamboh M Ilyas

Abstract excerpt

Genome-wide association studies (GWAS) have identified multiple type 2 diabetes (T2D) loci, mostly among populations of European descent. There is a high prevalence of T2D among Pakistanis. Both genetic and environmental factors may be responsible for this high prevalence. In order to understand the shared genetic basis of T2D among Pakistanis and Europeans, we examined 77 genome-wide significant variants...

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Share to Diabetes Mellitus, Type 2
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Genotyping Techniques

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Share to Polymorphism, Single Nucleotide

Share to Risk Assessment

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Identifiers

PMID: 33705809
DOI: 10.1016/j.gene.2021.145563

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