Article
Variants in KCNQ1 increase type II diabetes susceptibility in South Asians: a study of 3,310 subjects from India and the US.
BMC medical genetics - 24 Jan 2011
Been Latonya F, Ralhan Sarju, Wander Gurpreet S, Mehra Narinder K, Singh JaiRup, Mulvihill John J, Aston Christopher E, Sanghera Dharambir K
Abstract excerpt
BACKGROUND: Polymorphisms in intron 15 of potassium voltage-gated channel, KQT-like subfamily member 1 (KCNQ1) gene have been associated with type II diabetes (T2D) in Japanese genome-wide association studies (GWAS). More recently a meta-analysis of European GWAS has detected a new independent signal associated with T2D in intron 11 of the KCNQ1 gene. The purpose of this investigation is to examine the role of...
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