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Article

Otitis media: a genome-wide linkage scan with evidence of susceptibility loci within the 17q12 and 10q22.3 regions.

BMC medical genetics - 3 Sept 2009

Casselbrant Margaretha L, Mandel Ellen M, Jung Jeesun, Ferrell Robert E, Tekely Kathleen, Szatkiewicz Jin P, Ray Amrita, Weeks Daniel E

Abstract excerpt

BACKGROUND: Otitis media (OM) is a common worldwide pediatric health care problem that is known to be influenced by genetics. The objective of our study was to use linkage analysis to map possible OM susceptibility genes. METHODS: Using a stringent diagnostic model in which only those who underwent tympanostomy tube insertion at least once for recurrent/persistent OM are considered affected, we have carried out a...

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Identifiers

PMID: 19728873
DOI: 10.1186/1471-2350-10-85
PMCID: PMC2751750

Genes

SFTPA2
CCL5
IFNG
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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