Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

Free radical biology & medicine - 1 Jan 1990

Bandy B, Davison A J

Abstract excerpt

The sensitivity of mitochondrial DNA to damage by mutagens predisposes mitochondria to injury on exposure of cells to genotoxins or oxidative stress. Damage to the mitochondrial genome causing mutations or loss of mitochondrial gene products, or to some nuclear genes encoding mitochondrial membrane proteins, may accelerate release of reactive species of oxygen. Such aberrant mitochondria may contribute to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to DNA, Mitochondrial
Share to Mitochondria

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasms

Share to Oxygen

Source

Identifiers

PMID: 2193852
DOI: 10.1016/0891-5849(90)90152-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?PMID 2193852Read ↗

Mitochondrial DNA mutations, oxidative stress, and aging.Semantic proximity Read ↗

Mitochondrial DNA mutations and oxidative stress in mitochondrial diseases.Semantic proximity Read ↗

Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging.Semantic proximity Read ↗

Mitochondrial DNA alterations and reduced mitochondrial function in aging.Semantic proximity Read ↗

Mitochondrial DNA Mutagenesis: Feature of and Biomarker for Environmental Exposures and Aging.Semantic proximity Read ↗

Mitochondrial DNA Damage and DiseasesSemantic proximity Read ↗

Mitochondrial DNA Mutations and Ageing.Semantic proximity Read ↗

Mitochondrial DNA repair and aging.Semantic proximity Read ↗

Multiple Roles of Mitochondria in Aging ProcessesSemantic proximity Read ↗

Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging.Semantic proximity Read ↗

Role of mitochondrial DNA in toxic responses to oxidative stress.Semantic proximity Read ↗

Mitochondrial aging: open questions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.