Article
Genotypic resistance mutations to antiretroviral drugs in treatment-naive HIV/AIDS patients living in Liaoning Province, China: baseline prevalence and subtype-specific difference.
AIDS research and human retroviruses - 1 Mar 2007
Han Xiaoxu, Zhang Min, Dai Di, Wang Yanan, Zhang Zining, Liu Jing, Geng Wenqing, Jiang Yongjun, Takebe Yutaka, Shang Hong
Abstract excerpt
To examine the prevalence of drug resistance mutations among treatment-naive HIV/AIDS patients living in Liaoning province in China, the HIV-1 pol gene from plasma of 91 seropositive treatment-naive patients was amplified and sequenced. Three patients (3.3%) had an M46I amino acid substitution in the protease (PR) gene that decreased susceptibility to IDV, RTV, and NFV and one patient (1.1%) had an M184I amino...
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