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HIV type-1 genotypic resistance profiles in vertically infected patients from Argentina reveal an association between K103N+L100I and L74V mutations.

Antiviral therapy - 1 Jan 2010

Aulicino Paula C, Rocco Carlos A, Mecikovsky Debora, Bologna Rosa, Mangano Andrea, Sen Luisa

Abstract excerpt

BACKGROUND: Patterns and pathways of HIV type-1 (HIV-1) antiretroviral (ARV) drug resistance-associated mutations in clinical isolates are conditioned by ARV history and factors such as viral subtype and fitness. Our aim was to analyse the frequency and association of ARV drug resistance mutations in a group of long-term vertically infected patients from Argentina. METHODS: Plasma samples from 71 patients (38...

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PMID: 20587857
DOI: 10.3851/IMP1571

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