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Article

Target specificity of the Candida albicans Efg1 regulator

16 Sept 2011

Abstract excerpt

Efg1 is a central transcriptional regulator of morphogenesis and metabolism in Candida albicans. In vivo genome-wide ChIP chip and in vitro footprint analyses revealed the Efg1 recognition sequence (EGR-box) TATGCATA in the yeast growth form of this human fungal pathogen. Upstream regions of EFG1 and genes encoding transcriptional regulators of hyphal growth including TCC1, CZF1, TEC1, DEF1 and NRG1 contained...

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PMID: 21923768
DOI: 10.1111/j.1365-2958.2011.07837.x

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