Article
Transcriptional response of Candida albicans to hypoxia: linkage of oxygen sensing and Efg1p-regulatory networks.
Journal of molecular biology - 18 Aug 2006
Setiadi Eleonora R, Doedt Thomas, Cottier Fabien, Noffz Christine, Ernst Joachim F
Abstract excerpt
The major human fungal pathogen, Candida albicans, colonizes different body sites, differing greatly in oxygen levels. Using whole-genome DNA microarrays, we analysed the transcriptomal response of C. albicans to hypoxia. In this condition, transcripts of genes involved in fermentative metabolism, including glycolytic genes, as well as hypha-specific genes, were up-regulated; in contrast, genes regulating...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
