Article
Multiple HLA class I and II associations in classical Hodgkin lymphoma and EBV status defined subgroups.
Blood - 10 Nov 2011
Huang Xin, Kushekhar Kushi, Nolte Ilja, Kooistra Wierd, Visser Lydia, Bouwman Ilby, Kouprie Niels, Veenstra Rianne, van Imhoff Gustaaf, Olver Bianca, Houlston Richard S, Poppema Sibrand, Diepstra Arjan, Hepkema Bouke, van den Berg Anke
Abstract excerpt
The pathogenesis of classical Hodgkin lymphoma (cHL) involves environmental and genetic factors. To explore the role of the human leukocyte antigen (HLA) genes, we performed a case-control genotyping study in 338 Dutch cHL patients and more than 5000 controls using a PCR-based sequence-specific oligonucleotide probe hybridization approach. HLA-A68 and HLA-DR11 (5) were significantly increased in the cHL patient...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
